Entry 1 sense Webster, 1913 Assuetude · As·sue·tude · IPA /ˈæ.swɪˌtjuːd/ 01 n. Accustomedness; habit; habitual use. 1. Accustomedness; habit; habitual use. “Assuetude of things hurtful doth make them lose their force to hurt.” — Bacon.