Entry 1 sense Webster, 1913 Debilitation · De·bil·i·ta·tion · IPA /dɪbɪlɪˈteɪʃən/ 01 n. The act or process of debilitating, or the condition of one who is debilitated; weakness. 1. The act or process of debilitating, or the condition of one who is debilitated; weakness.