Entry 1 sense Webster, 1913 Disappearance /dĭsˌ-əp-ĭr'-əns/ · Dis·ap·pear·ance · IPA /dɪsəˈpɪəɹəns/ 01 n. The act of disappearing; cessation of appearance; removal from sight; vanishing. 1. The act of disappearing; cessation of appearance; removal from sight; vanishing.