Entry 1 sense Webster, 1913 Innervate /(ĭn*nẽr"vāt)/ · In·ner·vate · IPA /ɪˈnɝˌveɪt/ 01 v. t. To supply with nerves; as, the heart is innervated by pneumogastric and sympathetic branches. 1. To supply with nerves; as, the heart is innervated by pneumogastric and sympathetic branches.(Anat.)