Entry 2 senses · 2 variants Webster, 1913 Leese /(lēz)/ · IPA /liːz/ v. t. v. t. 01 v. t. To lose. 1. To lose.[Obs.] “They would rather leese their friend than their jest.” — Lord Burleigh. 02 v. t. To hurt. 1. To hurt.[Obs.]