Entry 2 senses Webster, 1913 Lycanthrope · Ly·can·thrope · IPA /ˈlaɪkənθɹoʊp/ 01 n. A human being fabled to have been changed into a wolf; a werewolf. 1. A human being fabled to have been changed into a wolf; a werewolf. 2. One affected with lycanthropy.