Entry 2 senses · 2 variants Webster, 1913 Mizzen · Miz·zen · IPA /ˈmɪ.zən/ a. n. 01 a. Hindmost; nearest the stern; as, the mizzen shrouds, sails, etc. 1. Hindmost; nearest the stern; as, the mizzen shrouds, sails, etc.(Naut.) 02 n. The hindmost of the fore and aft sails of a three-masted vessel; also, the spanker. 1. The hindmost of the fore and aft sails of a three-masted vessel; also, the spanker.(Naut.)