D defs.my
Entry 2 senses Webster, 1913

Omega

/(ō*mē"gȧ [or] ō*mā"gȧ [or] ō"mē̇*gȧ; 277)/ · O·me·ga · IPA /ˌoʊˈmeɪɡə/
01 n. The last letter of the Greek alphabet. See Alpha.
  1. 1.
    The last letter of the Greek alphabet. See Alpha. See: Alpha
  2. 2.
    The last; the end; hence, death.
    ““Omega! thou art Lord,” they said.” Tennyson.
    “The alpha and omega of science.” — Sir J. Herschel.
Phrases & compounds
Alpha and Omega — the beginning and the ending; hence, the chief, the whole.