Entry 2 senses · 2 variants Webster, 1913 Paregoric · Par·e·gor·ic · IPA /pɛɹɪˈɡɔɹɪk/ a. n. 01 a. Mitigating; assuaging or soothing pain; as, paregoric elixir. 1. Mitigating; assuaging or soothing pain; as, paregoric elixir. 02 n. A medicine that mitigates pain; an anodyne; specifically, camphorated tincture of opium; -- called also paregoric elexir. 1. A medicine that mitigates pain; an anodyne; specifically, camphorated tincture of opium; -- called also paregoric elexir.(Med.) Also: paregoric elexir