01 n. That which smites, wounds, or troubles; a blow; a calamity; any afflictive evil or torment; a great trail or vexation.
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2.
An acute malignant contagious fever, that often prevails in Egypt, Syria, and Turkey, and has at times visited the large cities of Europe with frightful mortality; hence, any pestilence; as, the great London plague.(Med.)
Phrases & compounds
Cattle plague —
See Rinderpest.
Plague mark —
a spot or mark of the plague; hence, a token of something incurable.