Entry 1 sense Webster, 1913 Regardful /(-f?l)/ · Re·gard·ful · IPA /ɹɪˈɡɑːdfʊl/ 01 a. Heedful; attentive; observant. 1. Heedful; attentive; observant. “Let a man be very tender and regardful of every pious motion made by the Spirit of God to his heart.” — South. Syn. Mindful; heedful; attentive; observant.