Entry 1 sense Webster, 1913 Soulless /sōl'-ləs/ · Soul·less · IPA /ˈsoʊl.ləs/ 01 a. Being without a soul, or without greatness or nobleness of mind; mean; spiritless. 1. Being without a soul, or without greatness or nobleness of mind; mean; spiritless. “Slave, souless villain, dog!” — Shak.