Entry 1 sense Webster, 1913 Thio- · Thi·o- · IPA /θaɪ.oʊ/ 01 A combining form (also used adjectively) denoting the presence of sulphur. See Sulpho-. 1. A combining form (also used adjectively) denoting the presence of sulphur. See Sulpho-.(Chem.) See: Sulpho-