Entry 2 senses · 2 variants Webster, 1913 Uncreate · Un·cre·ate · IPA /ˌʌnkɹiˈeɪt/ v. t. a. 01 v. t. To deprive of existence; to annihilate. 1. To deprive of existence; to annihilate. “Who can uncreate thee, thou shalt know.” — Milton. 02 a. Uncreated; self-existent. 1. Uncreated; self-existent.