D defs.my
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Entry 4 senses · 3 variants Webster, 1913

Despite

/dĭs-pīt'/ · De·spite · IPA /dɪˈspaɪt/
01 n. Malice; malignity; spite; malicious anger; contemptuous hate.
  1. 1.
    Malice; malignity; spite; malicious anger; contemptuous hate.
    “With all thy despite against the land of Israel.” — Ezek. xxv. 6.
  2. 2.
    An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt.
    “A despite done against the Most High.” — Milton.
Phrases & compounds
In despite — in defiance of another's power or inclination.
In despite of — in defiance of; in spite of. See under Spite.
In your despite — in defiance or contempt of you; in spite of you.
02 v. t. To vex; to annoy; to offend contemptuously.
imp. & p. p. Despited; p. pr. & vb. n. Despiting
  1. 1.
    To vex; to annoy; to offend contemptuously.[Obs.]
03 prep. In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.
  1. 1.
    In spite of; against, or in defiance of; notwithstanding; as, despite his prejudices.
Syn. See Notwithstanding.